Ampicillin is a bactericidal, semi-synthetic antibiotic derived from penicillin’s fundamental nucleus, 6-amino-penicillanic acid. Ampicillin exerts its bactericidal effect by preventing the synthesis of the bacterial cell wall and disrupting its integrity. Anhydrous Ampicillin is well absorbed by the gastrointestinal tract. After absorption, the volume of distribution of ampicillin is approximately 0,27 L/kg in dogs and 0,12 L/kg in cats; the biological half-life is approximately 48 minutes in dogs and 12 minutes in cats.
Ampicillin is usually well distributed by the organs. The excretion of ampicillin is renal and, after 6-8 hours, about 30% of the administered dose can be detected in the urine. It doesn’t present major metabolic changes and the product of excretion is the antibiotic itself. We can have considerable concentrations in bile, also representing a major route of elimination.
Ampicilina Veterinária Oral is a beta-lactam antibiotic belonging to the aminopenicillin group.
It is indicated for cats and dogs in the treatment of respiratory, genitourinary and gastrointestinal infections, in addition to other localized or systemic infections caused by:
• Dogs: Pasteurella multocida, Proteus mirabilis, Clostridium tetani, Escherichia coli, Klebsiella pneumoniae and Streptococcus zooepidemicu;
• Cats: Pasteurella multocida, Streptococcus canis, Proteus mirabilis, Clostridium tetani, Escherichia coli, Klebsiella pneumoniae, Streptococcus zooepidemicus and Leptospira interrogans.
To be used orally.
Preparation of the suspension: add potable water to the bottle, to approximately half of the height of the label, and shake vigorously until a homogeneous suspension is obtained. Next, fill up to the mark indicated on the label (60 mL), shaking again.
• Dogs and cats: administer 25 mg/kg body weight, or 1 mL of the reconstituted product for each kg of body weight, three times a day for 7 days.
|Ampicillin anhydrous||1,5 g|
|Excipient q.s.||50,0 g|
Bottle containing 50 g of powder for reconstitution.Where to buy?