Doxiciclina Vetnil Injectable Solution

Intravenous treatment of infections in dogs

Doxiciclina Vetnil Injectable Solution

Intravenous treatment of infections in dogs


PROPERTIES

Doxycycline is a highly lipophilic antibiotic of the tetracycline class, presenting greater distribution among tissues and facilitating the dosage for use.


Doxycycline is highly effective against other bacteria, including some strains of Staphylococcus.


It presents broad-spectrum bacteriostatic activity, acting through the inhibition of the protein system of sensitive microorganisms by reversible binding to the 30S subunits of the ribosome, which prevents the transporter RNA (tRNA) from joining the ribosome. Therefore, it damages the bacterial metabolism effectively.

 

INDICATION

Doxiciclina Vetnil Solución Inyectable is an antibiotic indicated for dogs in the treatment of infections caused by sensitive bacteria: Staphylococcus aureus, Staphylococcus pseudointermedius, Staphylococcus intermedius, Bordetella bronchiseptica, Corynebacterium auriscanis, Enterococcus faecalis, Streptococcus canis e Pasteurella multocida.

COMPOSITION

Each 100 mL contains:

Doxycycline hyclate  4,60 g*
Excipient q.s.  100 mL

*Equivalent to 4g of Doxycycline.

 

HOW TO USE

Product indicated for dogs in the dosage of 10 mg/kg once daily, intravenously, for a therapy period of up to 7 days. Administration should be slow and diluted in Physiological Solution or Lactated Ringer, in concentrations of maximum 20 to 30%, according to the following table:

Instructions for dose calculation:


1) Doxycycline base → 4% →
4 g/100 mL = 40 mg/mL


2) 10 mg/kg SID dose →
Therefore, 1 mL/4 kg = 0,25 mL/kg


3) For 20% →
1 part Doxycycline Vetnil Injectable Solution for 4 parts serum. Therefore, 1 mL of
product for each 4 mL of SF or RL.


4) For 30% →
3 parts Doxycycline Vetnil Injectable Solution for 7 parts serum. Therefore, 3 mL
for each 7 mL of SF or RL, or 1 mL for each 2,33 mL of SF or RL.

 

PRESENTATION

Bottle with 20 mL.

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